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Rather, it works through multiple distinct biological pathways that all converge to promote hair growth through the development of healthier and more robust hair follicles

[2] This suggests that MOTS-c is not merely a marker of youthful metabolism but may be an active contributor to the biological resilience that exceptional longevity requires

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It promotes neutrophil chemotaxis and degranulation leading to local inflammation in damaged tissues 37

Mice with inactivation of the urokinase plasminogen activator receptor (uPAR) gene, a key component of the HGF activation (Blasi, 1993), show diminished levels of HGF in cortical interneurons beginning at E16.5, indirectly suggesting that HGF has motogenic effects also on cortical interneuron precursors (Powell et al., 2001)