While NAD+ precursors (like NMN or NR) aim to increase NAD+ levels directly, 5-Amino-1MQ is studied for its upstream regulatory approachpotentially increasing NAD+ by blocking its consumption rather than adding more precursors
SNAP-GLP1R:CHO-K1 cells were incubated with LUXendin492 (LUX492), LUXendin551 (LUX551), and LUXendin615 (LUX615) before orthogonal SNAP-labeling with either cell-impermeable SBG-TMR or SBG-SiR and confocal imaging (nuclei were stained using Hoechst33342) (scale bar = 10 m) (n = three images from experiments performed in duplicate)
Safe for all skin types Non-toxic, no side effects
Casellini CM, Barlow PM, Rice AL, Casey M, Simmons K, Pittenger G, et al
If you are up for the task, you can also make your own fermented foods in the comfort of your own home