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GLP-1 receptor agonists typically achieve 5-15% body weight reduction depending on the specific agent and dose, with semaglutide generally producing the greatest weight loss
This review describes evidence from previous research on the effects of GLP-1R agonists on obesity
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Moreover, previous consideration of NMDA receptor antagonism as potential treatment for binge-eating disorder suggests that the weight-lowering benefits linked to GLP-1MK-801 could be the result of a combined impact on both energy homeostasis and disordered eating behaviours 10,14,41
J Endocrinol 116: 357-362, 1988
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