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Each component for the ternary complex formation was co-expressed in Trichoplusia ni cells (Expression systems) with a combination of individual baculoviruses as previously described 15

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Paxalisib showed the highest oral uptake (AUC_inf = 43,421.7 ngh mL 1 ) and sustained systemic presence, which was well represented in the NOCS (AUC_inf = 1140.9 nmol/Lh)