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The daily fermented foods of centenarian populations were delivering these compounds with a consistency and diversity that the unfermented diets of most modern populations simply do not provide

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Lifestyle interventions include regular aerobic exercise, weight loss for a BMI greater than 30, and sleep hygiene

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This chapter will systematically review the mechanisms, efficacy, neuro-specific advantages, and limitations of representative compounds and will further explore the unique challenges and future directions of optimizing ferroptosis-targeted therapies in the context of neurodegenerative disease