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Under conditions of hypoxia, nutrient deprivation, or impaired mitochondrial function, cancer cells modulate NADPH and GSH levels through key metabolic pathways such as the pentose phosphate pathway (PPP), FAO, and glutamine metabolism, thereby establishing a metabolicredox feedback loop [39,40,41]
Terpenoids as potential geroprotectors
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The present study found increased DNA methyltransferases activity and gene expression of Dnmt1, 3a, 3b, and Tet (2 and 3)
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