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The REDEFINE 3 cardiovascular outcomes trial which will take several years to complete is not a prerequisite for initial market authorisation for obesity treatment, but its results will likely be important for subsequent label expansion and for establishing the cardiovascular benefit profile that has proven so valuable for tirzepatide and semaglutide

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Since GLP 1 & GIP weight loss medications slow digestion, eating smaller meals spaced throughout the day rather than large meals can help prevent discomfort