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Together with HSP70 and HSP90, sHSPs form an integrated chaperone network that buffers neurons against proteotoxic stress, delays aggregate formation, and promotes clearance of damaged proteins
10.1038/335547a0 141 YuX.HeZ.WangZ.KeS.WangH.WangQ.et al (2024)
Hanson titled Alcohol Poisoning: Symptoms, Causes, and Prevention, published in the Journal of Alcohol and Drug Education (2017), a BAC above 0.40% carries a 50% mortality risk, especially without immediate medical intervention
xCT inhibition by sulfasalazine or through siRNA targeting SLC7A11 leads to reduced cell proliferation in vitro and in-vivo via reduction in GSH levels and an increase in ROS by inhibiting the CD44v9-SLC7A11 interaction (111, 113)
Neves JS, Borges-Canha M, Vasques-Novoa F, et al
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