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They also show promise for the treatment of many inflammatory diseases including asthma and inflammatory bowel disorders like Crohns disease and ulcerative colitis Diagram showing food stimulating the release of GLP-1 into the intestine and its effects on the brain, stomach and pancreas Importance In 2023 GLP-1 based drugs was named breakthrough of the year by Science , a prestigious American journal

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These medications should be avoided during pregnancy and breastfeeding, and women of reproductive potential should discontinue treatment at least 2 months before a planned pregnancy

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Some individuals notice increased fatigue, muscle tightness, or reduced recovery when intake becomes lower over time