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Such studies have shown that antibiotic administration might increase the effectiveness of L-DOPA therapy, indicating that gut microorganisms affect metabolism and the effectiveness of the drug (Hashim et al., 2014)
This leads to food staying in the stomach longer, keeping you feeling full and decreasing your appetite, which can lead to weight loss
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Once released, the GR amino acids that interact with the drug are Phe209, Ala319, Ile350 and Val354 at a distance of 2 to 4 and also with residues Tyr180, Leu321, Lys318, Leu320, and Thr352 (Thr352 forms several polar and hydrogen bonding interaction at 2.2 to 3.2 ) that stabilizes the carmustine in the binding pocket (Fig
