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Regulatory T (Treg) cells typically confer genetic resistance against organ-specific autoimmunity by actively suppressing the effector functions of self-antigen-reactive T cells, thereby inducing peripheral tolerance
Expected and unexpected effects of pharmacological antioxidants
When we feel "off" or notice our skin looking dull, it is often a signal that our internal systems are managing high levels of oxidative stress
The use of prodrugs activated in the hypoxic or acidic TME, as well as siRNA or antisense oligonucleotides delivered via MDSC-specific carriers, can further improve precision
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