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1GL), indicating that GSH inhibition is a key factor promoting the sensitivity of VRK2-deficient cells to APR-017 and LCS3

the dermatologically acceptable carrier or vehicle e.g., as a lotion, cream, ointment, soap, stick, or the like Humectants typically present in amounts ranging from about 0.1% to about 5% by weight of the total composition include, but are not limited to, polyhydric alcohols such as glycerol, polyalkylene glycols (e.g., butylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, and polyethylene glycol) and derivatives thereof, alkylene polyols and their derivatives, sorbitol, hydroxy sorbitol, hexylene glycol, 1,3-dibutylene glycol, 1,2,6-hexanetriol, ethoxylated glycerol, propoxylated glycerol, and mixtures thereof

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While no single supplement can entirely prevent heart attacks, glutathione plays a key role in reducing the oxidative stress that contributes to cardiovascular diseases