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Heartburn-related back pain typically occurs alongside classic acid reflux symptoms and may worsen after meals or when lying down

Variable filtering processes help mitigate these issues by transforming high-dimensional data into lower-dimensional forms while preserving variability [44]

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They do not address vaginal atrophy, hot flashes, or bone density on the timeline HRT does

Follow the dosage escalation in Table 1 to reduce the risk of gastrointestinal adverse reactions [see Warnings and Precautions (5.6), Adverse Reactions (6.1)]