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What matters most is having ongoing support to help them succeed with whichever approach makes sense for them." This is where clinical judgment matters

Have you noticed personality changes or depression since starting on GLP-1 drugs

Perhaps the better approach is to use an algorithm that includes gastric ultrasound, rapid sequence induction if GA is required, and greater use of clinical signs

But this is the reality of drug development (talking as a former CRA) Phase 3 trials take time, and they should take time, because thats how we ensure safety and efficacy at scale

Urinary sodium, potassium, and chloride were quantified by DRI-CHEM 800 (Fujifilm, Tokyo, Japan)