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Journal of diabetes research
PlexusDx recommends starting tirzepatide monotherapy first to establish tolerance and dosing stability
It is proposed to work by binding GHRH receptors on pituitary somatotroph cells, prompting the pituitary to synthesize and release its own growth hormone in a pulsatile pattern, with the body's somatostatin feedback loop still intact so the effect is self-limiting rather than a constant hormone flood
S.DruckerD
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