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It belongs to a new class: dual GLP-1/GIP agonists
Those with active hyperthyroidism should stabilize thyroid function first before adding weight loss therapy
Figure 1: A metabolic use-case comprehensive patient journey view with taXonomy Pathways In clinical trials, GLP-1 drugs showed high adherence (over 85% of patients stayed on therapy), yet real-world use tells a different story: one large study found only 32% of obese patients remained on a GLP-1 therapy after one year, with just 27% meeting standard adherence thresholds
That means a healthcare provider may wish to monitor thyroid hormone levels for patients who take a GLP-1 type alongside levothyroxine, regardless of if that GLP-1 is in an oral or injectable form
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