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Early Phase: Weeks 1 to 4 During the first four weeks, most users notice minimal visible changes
Paul, D., Verma, J., Banerjee, A., Konar, D
A lot of people find their way here after a first-generation GLP-1 stops doing what it did at the start: the early response tapers, the scale stalls, appetite creeps back
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What the data does change is the quality of the conversation around protocol design dose escalation, tolerability profiling, baseline BMI considerations, and the realistic expectation that meaningful weight reduction continues well past month six rather than plateauing at month three
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