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doi:10.1007/s40261-020-00958-8 McIntosh B, Cameron C, Singh SR, Yu C, Ahuja T, Welton NJ, Dahl M
A randomized, double-blind, placebo-controlled trial of deprenyl and thioctic acid in human immunodeficiency virus-associated cognitive impairment
FOXO4-DRI acts as a competitive inhibitor of this interaction binding directly to the transactivation domain 2 (TAD2) of p53, displacing FOXO4, and allowing phosphorylated p53 to be exported from the nucleus and directed to mitochondria, where it activates BAX, triggers caspase-3 cleavage (via the p53/BCL-2/Caspase-3 signalling pathway), and drives cell-intrinsic apoptosis
ScienceDirect, Harmon, D
Glutathione S-transferase polymorphisms, asthma susceptibility and confounding variables: a meta-analysis
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