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its strongest evidence base is in cardiac muscle, skeletal muscle, and skin wound healing models The combination is studied to investigate whether the two pathways exhibit additive or synergistic effects across tissue repair endpoints a question that would be difficult to study with either compound alone
Intramuscular injection delivers medication to deeper tissues and is used for longer-acting effects in some peptide protocols
Another study using NR supplementation showed that doses up to 1000 mg per day for 10 weeks were well tolerated in patients affected by mild cognitive impairments (MCI) 246
They may change depending on the composition and clinic
doi: 10.1089/acm.2006.12.857
