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Caplan and her team
10.1016/S1474-4422(14)70249-2 Lancet Neurol
Some patients maintain significant gastric emptying delay throughout treatment, whilst others develop near-complete tolerance to this effect
A few highlights: Accelerated eGFR decline during the year preceding a heart failure event Slower decline afterward but still exacerbated A parallel between eGFR slope and NYHA class, suggesting the kidney may be signaling congestion early These findings call for a shift in practice: instead of relying on static eGFR thresholds, tracking its trajectory over time could help us identify at-risk patients sooner and intervene before hospitalization
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