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Standard of Care) study for alogliptin (58, 62), the Savor-TIMI-53 study (Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes MellitusThrombolysis in Myocardial Infarction 53) for saxagliptin (60, 63), the TECOS study (Trial Evaluating Cardiovascular Outcomes With Sitagliptin) for sitagliptin (59, 64) and the CARMELINA study (Cardiovascular safety and Clinical Outcome with Linagliptin) for linagliptin (61, 65)

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It is a tripeptide thiol consisting of glutamic acid, glycine, and cysteine

For example, long-term starvation induces metabolic depression 102 , which compromises other fitness-related functions and lowers the animals capacity to cope with other stressors 28 , and hence metabolic adaptation is required to ensure survival

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