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discovered GPX4 as a selenoenzyme in 1985, making it the sole member of the PL-OOH scavenger family capable of turning harmful lipid hydroperoxides into harmless phosphatidyl alcohols ( in utero at mid-gestation ( On the other hand, different chemicals influence GPX4 synthesis at the post-transcriptional stage

Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p