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GLP-1, or glucagon-like peptide-1, is a hormone produced in the intestinal L-cells after eating
The risk goes up in certain situations
Upon ligand binding, conformational changes occur in the N-terminal ECD, leading to the activation of intracellular signaling cascades
Antiemetics (anti-nausea medications) like ondansetron are generally safe to use temporarily, but long-term masking of GLP-1 nausea may prevent proper dose titration
Proper spray technique, directing the spray toward the lateral nasal wall rather than straight back, minimizes posterior drainage
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